A new vaccine to protect against deadly cholera has been made by grinding up genetically modified grains of rice.
The first human trial has shown no obvious side effects and a good immune response.
Growing a new type of vaccine Vibrio cholerae bacteria is spread most often by drinking water contaminated with sewage.
Cholera infects 1.3 million to 4 million people and causes 21,000 to 143,000 deaths each year, according to the World Health Organization.
The new cholera vaccine grows in genetically modified Japanese short-grain rice plants that produce a nontoxic portion of CTB that can be recognized by the immune system.
"The rice protein bodies behave like a natural capsule to deliver the antigen to the gut immune system," said Dr. Kiyono.
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