The amended complaint adds the embattled Sackler family to the state's lawsuit against Purdue and its biggest competitors and distributors, including Johnson & Johnson and Cardinal Health.
New York says the defendants pushed doctors to issue prescriptions, lied about the risk of addiction and ignored red flags from suspicious pharmacies.
Meanwhile, states and local governments have targeted the Sackler family's wealth in an effort to recoup billions spent on the social costs of opioid addiction.
More than 1600 suits against opioid makers have been consolidated in federal court in Ohio, and other cases are pending in state courts.
The Sacklers have also been sued by a group of more than 500 cities and counties, in a case filed in New York, and the state of Massachusetts.
TOBY TALBOT/AP Purdue Pharma triggered a national addiction epidemic with its marketing of the Oxycontin painkiller, New York state alleges.
James also focused on Cardinal Health, which she said was the biggest distributor of opioid drugs in New York since 2010. »