Eggs not linked to cardiovascular risk, despite conflicting advice

Authored by sydney.edu.au and submitted by mvea
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University of Sydney researchers aim to help clear up conflicting dietary advice around egg consumption, as a new study finds eating up to 12 eggs per week for a year did not increase cardiovascular risk factors in people with pre-diabetes and type 2 diabetes.

Published in the American Journal of Clinical Nutrition today, the research extends on a previous study that found similar results over a period of three months.

Led by Dr Nick Fuller from the University’s Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders at the Charles Perkins Centre, the research was conducted with the University of Sydney’s Sydney Medical School and the Royal Prince Alfred Hospital.

In the initial trial, participants aimed to maintain their weight while embarking on a high-egg (12 eggs per week) or low-egg (less than two eggs per week) diet, with no difference in cardiovascular risk markers identified at the end of three months.

The same participants then embarked on a weight loss diet for an additional three months, while continuing their high or low egg consumption. For a further six months – up to 12 months in total – participants were followed up by researchers and continued their high or low egg intake.

At all stages, both groups showed no adverse changes in cardiovascular risk markers and achieved equivalent weight loss – regardless of their level of egg consumption, Dr Fuller explained.

oteds on May 8th, 2018 at 14:26 UTC »

And this article is sponsored by [insert egg company]

Askray184 on May 8th, 2018 at 12:56 UTC »

2 eggs a day is not many... what about more than that? 6 a day? 12? 48?

mvea on May 8th, 2018 at 11:07 UTC »

The title of the post is a copy and paste from the first paragraph of the linked academic press release here:

Eating up to 12 eggs a week does not increase cardiovascular risk factors in people with pre-diabetes or type 2 diabetes, new research finds – despite conflicting dietary advice continuing around the world.

Journal Reference:

Nicholas R Fuller, Amanda Sainsbury, Ian D Caterson, Gareth Denyer, Mackenzie Fong, James Gerofi, Chloris Leung, Namson S Lau, Kathryn H Williams, Andrzej S Januszewski, Alicia J Jenkins, Tania P Markovic.

Effect of a high-egg diet on cardiometabolic risk factors in people with type 2 diabetes: the Diabetes and Egg (DIABEGG) Study—randomized weight-loss and follow-up phase.

The American Journal of Clinical Nutrition, 2018;

DOI: 10.1093/ajcn/nqy048

Link: https://academic.oup.com/ajcn/advance-article-abstract/doi/10.1093/ajcn/nqy048/4992612?redirectedFrom=fulltext

Abstract

Background

Some country guidelines recommend that people with type 2 diabetes (T2D) limit their consumption of eggs and cholesterol. Our previously published 3-mo weight-maintenance study showed that a high-egg (≥12 eggs/wk) diet compared with a low-egg diet (<2 eggs/wk) did not have adverse effects on cardiometabolic risk factors in adults with T2D.

Objective

The current study follows the previously published 3-mo weight-maintenance study and assessed the effects of the high-egg compared with the low-egg diets as part of a 3-mo weight-loss period, followed by a 6-mo follow-up period for a total duration of 12 mo.

Design

Participants with prediabetes or T2D (n = 128) were prescribed a 3-mo daily energy restriction of 2.1 MJ and a macronutrient-matched diet and instructed on specific types and quantities of foods to be consumed, with an emphasis on replacing saturated fats with monounsaturated and polyunsaturated fats. Participants were followed up at the 9- and 12-mo visits.

Results

From 3 to 12 mo the weight loss was similar (high-egg compared with low-egg diets: −3.1 ± 6.3 compared with −3.1 ± 5.2 kg; P = 0.48). There were no differences between groups in glycemia (plasma glucose, glycated hemoglobin, 1,5-anhydroglucitol), traditional serum lipids, markers of inflammation [high-sensitivity C-reactive protein, interleukin 6, soluble E-selectin (sE-Selectin)], oxidative stress (F2-isoprostanes), or adiponectin from 3 to 12 mo or from 0 to 12 mo.

Conclusions

People with prediabetes or T2D who consumed a 3-mo high-egg weight-loss diet with a 6-mo follow-up exhibited no adverse changes in cardiometabolic markers compared with those who consumed a low-egg weight-loss diet. A healthy diet based on population guidelines and including more eggs than currently recommended by some countries may be safely consumed. This trial is registered at http://www.anzctr.org.au/ as ACTRN12612001266853.