A worsening epidemic of diabetes and its precursor, metabolic syndrome (MetS) is engulfing America. A healthy individual, with proper glucose regulation has an ability to switch between burning fat and carbohydrates. It has been suggested that signaling errors within this homeostatic system, characterized by impaired switching of substrate oxidation from glucose to fat in response to insulin, can contribute to the etiology of metabolic syndrome and occurs before the development of type II diabetes.
Glucose regulation with restored insulin sensitivity facilitated through clinically regulated, benign dietary ketosis (BDK), may significantly reduce, regulate and reverse the adverse pathologies common to MetS and obesity. The study assessed if prolonged maintenance of induced and controlled physiological, dietary ketosis, would reverse pathological processes induced by MetS including a reduction in fasting triglycerides, BMI (body mass index) and body fat mass (BFM), weight, a significant decrease and/or normalization of hemoglobin A1c (HgA1c) and an increase in resting metabolic rate (RMR) and blood ketones. A group of 30 adults, previously diagnosed with MetS by their primary care physician, were randomly prescribed to one of three groups: a sustained ketogenic diet with no exercise, standard American diet (SAD) with no exercise or SAD with 3-5 days per week of exercise (30 min.). The results demonstrated that the change over time from week 0 to week 10 was significant (p = 0.001) in the ketogenic group for weight, body fat percentage, BMI, HgA1c and ketones. All variables for the ketogenic group out-performed those of the exercise and non-exercise groups, with five of the seven demonstrating statistical significance.
MustGoOutside on December 5th, 2017 at 22:10 UTC »
I am frustrated that there is no mention of caloric intake for each diet, unless I am missing an exhibit on the page.
Is the SAD diet prescribed the same number of total calories as the Keto diet?
Since this is focused on weight loss, as well as the type of weight, the caloric intake is a crucial figure.
IamKabr on December 5th, 2017 at 21:43 UTC »
I find their choice to include no dietary data highly suspect. Without information regarding what and how much the participants were eating, its hard to truly know the weight of the researcher's findings. In the discussion, they mention the methodology of other studies, but never get into their own. The paper doesn't indicate that the participants were taught how measure their food, or if meals were prepared for them. If the meals where not prepared and distributed by the researchers, were the participants taught how to track their intake? A lesser point, but when were the participants eating?
HighOnGoofballs on December 5th, 2017 at 20:25 UTC »
Was the "standard diet" also running a caloric deficit? I looked but couldn't tell.