## Stanford scientists regrow lost cartilage and reverse arthritis in major breakthrough

Authored by sciencedaily.com

A treatment that targets a protein linked to aging has restored lost knee cartilage in older mice and prevented arthritis from developing after serious joint injuries, according to a Stanford Medicine-led study.

Osteoarthritis is the most common form of arthritis and affects about one in five adults in the United States.

Previous studies showed that 15-PGDH plays a major role in age-related muscle decline in mice.

Scientists have also linked 15-PGDH to the regeneration of bone, nerve, and blood cells.

While researchers have identified possible cartilage-producing stem cells in bone, similar cells have not been successfully identified in articular cartilage.

Our hope is that a similar trial will be launched soon to test its effect in cartilage regeneration.

Blau, Bhutani, and several co-authors are inventors on Stanford University patent applications involving 15-PGDH inhibition for cartilage repair and tissue rejuvenation that have been licensed to Epirium Bio. »

### German minister blames Trump for Strait of Hormuz closure

Authored by straitstimes.com

BERLIN - German Defence Minister Boris Pistorius on June 21 blamed US President Donald Trump for the closure of the Strait of Hormuz, calling for the vital waterway to be reopened.

The minister added that any agreement to reopen the strait would need the support of Iran and Oman.

When Trump pressed allies to help re-open or secure the Strait of Hormuz in April, German Chancellor Friedrich Merz said the war was “not a matter for NATO”. »

### Concerns over therapy ferrets used to kill rats at UK’s largest children’s prison

Authored by theguardian.com

Pet ferrets kept as therapy animals at the UK’s largest children’s prison have been co-opted by managers to kill rats, resulting in a bloody incident and concerns over child and animal welfare.

But in mid-May, staff and children complained about dozens of rats running around the grounds and inside prison buildings.

Prison Service sources blamed the influx of rats at Wetherby on building work disturbing a rats’ nest. »

### Montreal mayor says husband, who is Black, was stopped last year 'at least 5 or 6 times — for nothing'

Authored by cbc.ca

Montreal Mayor Soraya Martinez Ferrada says a moratorium on police checks would be a “good first step” in helping address allegations of racism within the city’s police service.

The 2024 data shows that, in Montreal, Black people are four times more likely to be stopped than white individuals, while Arab people are five times more likely to be stopped.

The call comes after Montreal police confirmed that 16 officers based in Montréal-Nord are under investigation for alleged co-ordinated racist behaviour. »

### Trump Does Not Understand the War He Lost

Authored by theatlantic.com

Donald Trump arrived in France yesterday for this morning’s G7 summit and promptly confirmed America’s capitulation to Iran.

Just this winter, Trump had promised the Iranian people that the tyrants who ruled them would be gone.

In the past, Trump has tried to conjure new circumstances by speaking them aloud and attempting to wish them into existence. »

## In pictures

## Also in the news

#### US farmer faces legal pushback for paying white SA workers higher wages

#### Germany backs EU’s tough China line with call for ‘Plaza Accord’ talks on yuan

#### Far-right millionaire wins Colombia’s razor-tight presidential election

#### Diagnosed with Stage 4 cancer and given just 8 months to live, a teen beat the odds thanks to an extraordinary friendship

#### Vance lands in Switzerland for Iran talks as Trump threatens 'harder' strikes