The Daily Populous Saturday May 2nd, 2026 morning edition
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A federal appeals court has restricted access to one of the most common means of abortion in the U.S. by blocking the mailing of mifepristone prescriptions.

Friday’s unanimous ruling from a three-judge panel of the New Orleans-based 5th U.S. Circuit Court of Appeals is requiring that the abortion pill be distributed only in person and at clinics, overruling regulations set by the federal Food and Drug Administration.

The ruling, which is likely to be appealed to the U.S. Supreme Court, is the biggest jolt to abortion policy in the U.S. since the 2022 Supreme Court ruling that overturned Roe v. Wade and allowed states to enforce abortion bans.

In the ruling, Judge Kyle Duncan, who was appointed by President Donald Trump, agreed with the state of Louisiana’s contention that allowing the drug to be mailed there makes moot the state’s ban on abortion at all stages of pregnancy.

“Every abortion facilitated by FDA’s action cancels Louisiana’s ban on medical abortions and undermines its policy that ‘every unborn child is human being from the moment of conception and is, therefore, a legal person,’” the ruling states.

Mifepristone is involved in most abortions in the US

Mifepristone was approved in 2000 as a safe and effective way to end early pregnancies. It is typically used in combination with a second drug, misoprostol.

Surveys have found that the majority of abortions in the U.S. are provided via pills and that about 1 in 4 abortions nationally are prescribed via telehealth.

One survey of abortion providers last year estimated that more women in states where abortion is banned obtained abortions that way than by traveling to other states.

Some Democratic-led states have laws that seek to protect providers who prescribe via telehealth to patients in places with bans.

That rise in prominence is why abortion opponents have targeted the pills in legislation and litigation.

Ruling goes against how courts usually view FDA decisions

There is little precedent for a federal court overruling the scientific regulations of the FDA, and it wasn’t immediately clear how quickly or completely the decision would impact mailing of the drug throughout the country.

Judges have long deferred to the agency’s judgments on the safety and appropriate regulation of drugs.

FDA officials under Trump have repeatedly stated that the agency is conducting a new review of mifepristone’s safety, at the direction of the president.

The judges, all nominated by Republican presidents, noted in their ruling that the FDA “could not say when that review might be complete and admitted it was still collecting data.”

Because of rare cases of excessive bleeding, the FDA initially imposed strict limits on who could prescribe and distribute the pill — only specially certified physicians and only after an in-person appointment where the person would receive the pill.

Both those requirements were dropped during the COVID-19 years. At the time, FDA officials under President Joe Biden said that after more than 20 years of monitoring mifepristone use, and reviewing dozens of studies involving thousands of women, it was clear that women could safely use the pill without direct supervision.

GenBioPro, which makes generic mifepristone, said in a statement the court’s decision “ignores the FDA’s rigorous science and decades of safe use of mifepristone in a case pursued by extremist abortion opponents.”

The impact isn’t just in states with bans

In a court filing, Louisiana’s attorney general and a woman who said she was coerced into taking abortion pills requested that the FDA rules be rolled back to when the pills were allowed to be prescribed and dispensed only in person.

A Louisiana-based federal judge last month ruled that those allowances undermined the state’s abortion ban but stopped short of undoing the regulations immediately.

Friday’s ruling is in effect as the case works its way through the courts and extends beyond Louisiana and states with abortion bans.

Telehealth prescriptions have become common even in states where abortion is allowed — and the ruling blocks them there, too.

“This is going to affect patients’ access to abortion and miscarriage care in every state in the nation,” said Julia Kaye, an ACLU lawyer. “When telemedicine is restricted, rural communities, people with low incomes, people with disabilities, survivors of intimate partner violence and communities of color suffer the most.”

The National Right to Life Committee said the ruling “restores a critical layer of oversight” in women’s health.

“Women deserve better than an abortion-by-mail system that prioritizes ideology over safety,” said Carol Tobias, the group’s president.

Next step could be an appeal to the nation’s top court

Danco Laboratories, another mifepristone manufacturer and a defendant in the lawsuit, asked the appeals court Friday after the ruling to put its order on hold for one week to give the company time to “seek relief” from the Supreme Court. If the court does not grant the request, the company said it will file an emergency appeal with the high court.

The conservative-majority Supreme Court overturned abortion as a nationwide right in 2022 but unanimously preserved access to mifepristone two years later.

That 2024 decision sidestepped the core issues, however, by ruling that the anti-abortion doctors behind the case didn’t have legal standing to sue.

“I look forward to continuing to defend women and babies as this case continues,” Louisiana Attorney General Liz Murrill, a Republican, said in a statement.

Representatives for the FDA and the U.S. Department of Justice did not immediately respond to requests for comment Friday evening.

In the meantime, anti-abortion groups are celebrating Friday’s ruling. Marjorie Dannenfelser, president of Susan B. Anthony Pro-Life America, applauded the ruling as “a huge victory for victims and survivors of Biden’s reckless mail-order abortion drug regime.” She also criticized the Trump administration for taking time to conduct its own review of mifepristone, saying its slow movement has forced states to take action.

“Women and children suffer and state sovereignty is violated every day the FDA allows abortion drugs to flood the mail,” Dannenfelser said.

Associated Press reporters John Hanna, Matthew Perrone and Lindsay Whitehurst contributed.

danappropriate on May 1st, 2026 at 22:22 UTC »

The 5th Circuit. Of course.

Grant_Winner_Extra on May 1st, 2026 at 22:14 UTC »

The 5th circuit is the most-overturned circuit and they’ve tried this a half dozen times already. It will get overturned and even if it doesn’t, it only applies in the 5th circuit.

Mediocre_Ad_4649 on May 1st, 2026 at 22:14 UTC »

I thought nationwide injunctions can't be issued anymore? So wouldn't this "only" apply to the fifth district?