US Secretary of State Marco Rubio on Monday voiced hope for working with elements within Iran's government, saying the United States privately had received positive messages.
Rubio said there were internal "fractures" inside the country and that the United States hopes figures with "power to deliver" take charge.
In a separate interview with Al Jazeera, Rubio said there were "messages and some direct talks going on between some inside of Iran and the United States.".
Iran denies seeking a nuclear weapon and the UN nuclear watchdog has said no bomb was imminent.
Rubio's comments came a day after Trump said that Iran has already gone through "regime change," one month into the war launched by the United States and Israel.
On the first day of the war Israel assassinated Iran's longtime supreme leader, Ali Khamenei, and subsequent strikes have killed other top leaders.
Rubio said that there was a difference between private and public messages coming from Iran. »