## New study shows Alzheimer’s disease can be reversed to achieve full neurological recovery—not just prevented or slowed—in animal models

Authored by case.edu

Despite billions of dollars spent on decades of research, there has never been a clinical trial of any drug to reverse and recover from AD.

The study, led by Kalyani Chaubey, from the Pieper Laboratory, was published online Dec. 22 in Cell Reports Medicine.

Without proper NAD+ balance, cells eventually become unable to execute many of the critical processes required for proper functioning and survival.

The researchers used two of these mouse models: One carried multiple human mutations in amyloid processing; the other carried a human mutation in the tau protein.

The results prompt a paradigm shift in how researchers, clinicians and patients can think about treating AD in the future.

“The key takeaway is a message of hope—the effects of Alzheimer's disease may not be inevitably permanent,” Pieper said.

Pieper emphasized that current over-the-counter NAD+-precursors have been shown in animal models to raise cellular NAD+ to dangerously high levels that promote cancer. »

### Minnesota Hilton cancels ICE agents’ hotel reservations

Authored by theguardian.com

After ICE officers booked rooms using official government emails and rates, Hilton canceled their reservations, the department said in a post on X.

In a statement, a Hilton spokesperson said the brand’s hotels “serve as welcoming places for all” and that the hotel that canceled the reservations was independently owned and operated.

Everpeak Hospitality, the owner of the hotel, said it had “moved swiftly to address this matter” and that it was “inconsistent” with hotel policy. »

### Robot Dogs With Elon Musk and Mark Zuckerberg’s Faces Poop Out AI Art

Authored by scienceclock.com

Then one of them stops, leans back slightly, and prints an image from its rear while a small screen flashes “POOP MODE.”.

Some resemble tech billionaires such as Elon Musk, Mark Zuckerberg, and Jeff Bezos.

An Art Basel installation featuring robot dogs with wax heads of Jeff Bezos, Elon Musk and Mark Zuckerberg went viral as it examined how tech leaders influence how we see the world. pic.twitter.com/759m7271nb — The Associated Press (@AP) December 5, 2025. »

### RFK Jr. overhauls childhood vaccine schedule to resemble Denmark's in unprecedented move

Authored by nbcnews.com

The Centers for Disease Control and Prevention on Monday announced an unprecedented overhaul of the childhood vaccine schedule that recommends fewer shots to all children.

Under the change — effective immediately — the vaccine schedule will more closely resemble Denmark’s, recommending all children get vaccines for 11 diseases, compared with the 18 previously on the schedule.

“It’s really the most significant weakening of childhood vaccine recommendations, I would say, in modern American history,” he said. »

### After decades of teaching media literacy, Finland equips students with skills to spot AI deepfakes

Authored by euronews.com

For decades, the Nordic nation has woven media literacy, including the ability to analyse different kinds of media and recognise disinformation, into its national curriculum for students as young as 3 years old.

"We think that having good media literacy skills is a very big civic skill," said Kiia Hakkala, a pedagogical specialist for the City of Helsinki.

Vanhanen said his students have been learning about fake news and disinformation for years, beginning with reading headlines and short texts. »

## In pictures

## Also in the news

#### Reports of gunfire near Venezuela’s presidential palace

#### Corporation for Public Broadcasting votes itself out of existence

#### US attack on Greenland would mean end of Nato, says Danish PM

#### US-based multinational companies will be exempt from global tax deal

#### CDC cuts universal child vaccine recommendations, including covid and hepatitis