## First human trial of regenerative cell therapy for sensorineural hearing loss approved

Authored by openaccessgovernment.org

The University of Sheffield announces approval of the first human trial testing regenerative cell therapy to treat sensorineural hearing loss, offering hope for restoring hearing function.

Researchers at the University of Sheffield are set to begin the first-ever human trial exploring regenerative cell therapy as a treatment for sensorineural hearing loss.

Rinri Therapeutics, a leading University of Sheffield spin-out company dedicated to transforming the treatment of sensorineural hearing loss with a regenerative cell therapy, has received approval from the UK’s Medicines and Healthcare products Regulatory Agency (MHRA) to begin its first-in-human clinical trial.

Sensorineural hearing loss happens when the sensitive, hair-like cells within the cochlea or the hearing nerve become damaged.

The clinical trial will take place at three leading hearing research centres in the UK and will operate as a randomised, open-label trial.

The trial will involve 20 patients undergoing cochlear implantation for hearing loss, with ten patients having postsynaptic auditory neuropathy spectrum disorder (ANSD) and ten having severe-to-profound age-related hearing loss (presbycusis).

Simon Chandler, CEO of Rinri Therapeutics, said: “Approval to start our first clinical trial with Rincell-1 in hearing loss is a major milestone and recognition of the potential of our regenerative cell therapy in this area of significant unmet medical need. »

### A new diabetes treatment could free people from insulin injections

Authored by sciencenews.org

A new therapy for type 1 diabetes could nix the need for insulin injections.

A year after treatment, 10 out of 12 participants no longer needed supplemental insulin.

“Coming off insulin therapy is a remarkable achievement,” says Tom Donner, director of the Johns Hopkins Diabetes Center. »

### The U.S. Is Switching Sides

Authored by theatlantic.com

Donald Trump repeatedly promised, during his campaign, that he would end the war “in one day,” but the war is not over.

He spoke to Vladimir Putin yesterday, and Putin responded with more drones and missiles than ever before.

The U.S. could still expand sanctions on Russia, provide ammunition, and help the Ukrainians win the narrative war. »

### Chinese Inventor Builds Motorized Bed on Wheels so He Never Has to Leave It

Authored by utubepublisher.in

In a fun twist on staying in bed all day, a man from China has taken it to a whole new level.

He retrofitted his mattress with a joystick controlled motor and wheels, creating a mobile bed that moves at the pace of walking.

He’s essentially blended furniture design with electric vehicle engineering and done it all with a sense of laid back flair. »

### Trump Apparently Didn’t Know His Own Bill’s Extreme Medicaid Plan

Authored by newrepublic.com

NOTUS reported on Wednesday that House Republicans had to tell the president that his “big, beautiful bill” was indeed slashing Medicaid.

Trump has never been the wonkiest guy, but the fact that he was seemingly unaware that his “big, beautiful bill” is attacking Medicaid is alarming.

It’s not that Trump didn’t understand that, it’s that he didn’t seem to know that was happening at all. »

## In pictures

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