German rail operator Deutsche Bahn said four platforms at the station were closed and some services would experience delays and diversions.
Pictures from the scene show a number of emergency service personnel and vehicles on the ground, and barriers that seem to be hiding the injured from public view.
One photograph used by German media shows a man being taken away by paramedics on a stretcher.
A video on social media appears to show the suspect with her hands behind her back being escorted out of the station platform by officers who put her in a police vehicle.
Hamburg Central Station is one of Germany's busiest transport hubs, with more than 550,000 travellers per day according to its website. It is often crowded during Friday rush hour.
This is the latest in a series of violent attacks in Germany in recent months.
In January, a two-year-old boy and a 41-year-old man were killed in a stabbing in a park in Aschaffenburg, with several others hurt.
A Spanish tourist was stabbed just a month later at Berlin's Holocaust Memorial.
Last December, six people were killed and hundreds were injured after a car drove into a crowd at a Christmas market in the eastern city of Magdeburg.
The suspects in these previous attacks were migrants, which has led Germany to tighten border control checks and saw immigration become a key issue for voters during the country's federal elections in February.
13rajm on May 23rd, 2025 at 19:09 UTC »
Women in male dominated fields
fxkatt on May 23rd, 2025 at 18:22 UTC »
A spokesman for the Hamburg fire department told Agence France-Presse (AFP) that 12 people had been injured in the attack. Among them were "six people with life-threatening injuries," the spokesman said.
This account makes the attack more deadly than the earlier one
kane49 on May 23rd, 2025 at 18:16 UTC »
thats certainly a statement