The psychedelic state induced by LSD appears to weaken the association between anatomical brain structure and functional connectivity, according to new research published in the journal NeuroImage.
The study also provides evidence that LSD increases the complexity of segregated brain states.
The findings provide new insights into the relationship between brain function and consciousness.
But we think that a complementary way to obtain insights is to study states of altered consciousness, such as the psychedelic state induced by LSD.”.
Luppi and his colleagues used functional magnetic resonance imaging (fMRI) to examine the structural and functional brain connectivity of 15 healthy volunteers during two separate sessions.
Our research shows that under the effects of LSD, this relationship becomes weaker: function is less constrained by structure.
In addition, these changes in brain integration and segregation fluctuated over time, and these fluctuations were associated with subjective experiences. »