The Daily Populous

Friday November 6th, 2020 evening edition

image for Human recombinant soluble ACE2 (hrsACE2) shows promise for treating severe COVID­19

Notably, the use of hrsACE2 did not impede the generation of neutralizing antibodies, leading to a significant clinical improvement of the treated patient.

A pandemic spread of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for more than one million deaths due to COVID-19.

ACE2 is a transmembrane protein typically known for its carboxypeptidase activity and its physiological role in the renin-angiotensin system.

ACE2 hydrolyzes angiotensin II to its metabolite, angiotensin 1–7 and angiotensin I to angiotensin 1–9 to protect diverse tissues from injury (Fig.

1 Schematic diagram of the renin-angiotensin system and the proposed therapeutic treatment for COVID-19 targeting SARS-CoV-2 viral entry mechanism.

(Left) The receptor-binding domain (RBD) of the spike protein from SARS-CoV-2 binds to ACE2, allowing host cell entry and infection.

ADAM17 cleaves the extracellular juxta-membrane region of ACE2, whether such ACE2 cleavage contributes to SARS pathogenesis is not known yet. »

Stacey Abrams Says 'My Heart is Full' As Georgia Poised to Turn Blue For First Time in 28 Years

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Posting on social media on Friday morning, Abrams praised several Georgia nonprofits, the local Democratic Party branch and the late Congressman John Lewis as Biden appeared poised to turn Georgia blue for the first time in almost three decades.

My heart is full," Abrams tweeted this morning.

"Georgia, let's shout out those who've been in the trenches and deserve the plaudits for change.". »

Trump aides reportedly had to explain to the president that his demand to 'STOP THE COUNT' would actually guarantee his loss

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The president has since called for counting to stop, baselessly taking issue with the legality of counting mail-in ballots after Election Day.

After the explanation, the aides persuaded Trump to tweet "stop the fraud" instead, both The Post and NBC News reported.

Biden moved ahead of Trump in Georgia, was leading in Nevada and Arizona, and was narrowing Trump's lead in Pennsylvania. »

The day the world stopped paying attention to Donald Trump

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Attention — the fear of being on the receiving end of a mean tweet — kept a lot of GOP elected officials in line.

"For GOPers to not stand up now shows your true colors," Donald Trump Jr. wrote on Twitter.

For five years now, Donald Trump has sucked all the air out of the room, absorbing our attention and occupying our thoughts. »

Joe Biden Has Taken The Lead In The Historically Red State Of Georgia

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Joe Biden on Friday pulled ahead of President Donald Trump in Georgia, setting the stage for him to become the first Democrat to win the state since 1992.

Biden leads by only 1,096 votes out of 4.9 million total votes tallied, with at least 8,000 votes left to count.

Georgia Secretary of State Brad Raffensperger said late Friday morning that there will be a recount. »