Israeli doctor reinfected with coronavirus 3 months after recovering

Authored by jpost.com and submitted by thewrongun
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A doctor at Sheba Medical Center in Tel Hashomer tested positive again for the novel coronavirus three months after initially recovering from the disease.

The doctor “tested positive again because she has remnants of her first virus still floating around in her body,” a hospital spokesperson told The Jerusalem Post on Sunday.

The doctor suffered from fever, cough and muscle pain when she tested positive for the virus in April, but she recovered and tested negative in May and June.

Earlier this month, she came in contact with a confirmed patient and subsequently tested positive for the virus.

The cases are the latest in a series of incidents of suspected reinfection that have raised questions concerning how long immunity against the virus lasts.

In May, a 45-year-old woman from Jisr e-Zarka tested positive for coronavirus after being readmitted to Hillel Yaffe Medical Center in Hadera, suffering from fever and chest pains. This came a month after she was discharged after recovering from the virus and testing negative twice.

Several studies are attempting to figure out how long protection provided by antibodies will last, Dr. Maria van Kerkhove, the World Health Organization’s COVID-19 technical lead, said last week, adding that some initial studies have found they “may wane after a couple of months.”

With coronaviruses such as SARS and MERS, people had some form of immunity for about a year or even longer, but with other human coronaviruses that circulate regularly, the immunity period is much shorter, Kerkhove said. This is “early data,” and more studies are needed, she said.

Preliminary studies in China, Germany, the UK and elsewhere have found patients infected with the novel coronavirus make protective antibodies as part of their immune system’s defenses, but these appear to last only a few months.

That raises big problems for developers of potential COVID-19 vaccines, experts say, and for public health authorities seeking to deploy them to protect populations from future waves of the pandemic.

To be truly effective, COVID-19 vaccines “will either need to generate stronger and longer-lasting protection... or they may need to be given regularly,” said Stephen Griffin, a Leeds University associate professor of medicine. “And those things are not trivial.”

Celia Jean and Reuters contributed to this report.

Masculinum on July 19th, 2020 at 20:55 UTC »

The doctor “tested positive again because she has remnants of her first virus still floating around in her body,” a hospital spokesperson told The Jerusalem Post on Sunday.

From the article

captainmcfuckface on July 19th, 2020 at 18:58 UTC »

why is there never details with reinfections? I want to know are reinfections lighter, worse, equal? Cold viruses, which are much closer to COVID19 than influenza, reinfect constantly, but usually the body gets routine about licking it quick until a new strain hits it. Is that the case with COVID 19? Or it it full force each time. I can not find one god damn detail on this

Mantstarchester on July 19th, 2020 at 17:40 UTC »

It's important to note that when scientists and doctors speak about "immunity", it's really more of a "resistance" they're referring to.

Let's say I was vaccinated against the flu, and my body successfully made antibodies to the flu antigens. That may very well protect me in day-to-day exposures of the flu. However, it doesn't mean it's impossible for me to be infected. Suppose someone gave me a massive bolus of flu virus right into my sinuses. Even with my antibodies, it's possible that I could still experience an infection.

The same could be true here. A doctor intubating COVID patients throughout the day could be exposed to seriously massive doses of the SARS-COV-2 virus. That could overwhelm the protection their antibodies confer, resulting in another infection. Combine this with the recent reports of a dramatic loss of COVID antibodies in the months following infection, and I think it's reasonable to think that reinfection is likely. Assuming, of course, that this is a case of true reinfection and not of false positive tests.

Edit: As others have pointed out, memory B cells should allow for a quicker response to the infection following another exposure. There is also the very real possibility of a latent infection, and that this person is still testing positive from their initial infection. Even if reinfection is possible in theory, for the vast majority of people, it doesn't seem likely. Take that in combination with the high titers of neutralizing antibodies seen in the vaccine trials (Namely AZ/Oxford), and I'm optimistic for a successful vaccine candidate.