Childhood poverty has a lasting impact on developing brain, finds study

Authored by independent.co.uk and submitted by mvea
image for Childhood poverty has a lasting impact on developing brain, finds study

Growing up in a less well-off family may negatively impact the brain, according to research showing how socioeconomic status can have a lasting impact on a person’s development.

US researchers found brain regions responsible for learning, language and emotional development tended to be more complex in people whose parents were educated to a higher level or who worked in professional rather than manual jobs.

Brain scans from hundreds of young people show these effects are stable throughout childhood and adolescence, the National Institute of Mental Health researchers found.

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This means targeting additional support in the pre-school years could help minimise inequalities it causes in a host of life outcomes, including mental health and academic achievement, the researchers added.

“Early brain development occurs within the context of each child’s experiences and environment, which both vary significantly as a function of socioeconomic status,” said lead author Cassidy McDermott and colleagues.

In childhood, socioeconomic status, which encompasses income as well as opportunities and a string of other factors, has been linked to a range of mental health, cognitive development, and academic outcomes.

“Socioeconomic status may exert some of its effect on cognition by altering structural brain development, particularly in regions associated with language and learning,” Ms McDermott said.

“However, it is important to note that this pathway represents only one possible set of interactions between childhood environment, anatomy, and cognition.”

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For the study, published in the Journal of Neuroscience, the researchers looked at 1,243 brain MRI scans from more than 623 young people aged between five and 25. While the socioeconomic score used did not take account of family income in the earliest measurements this is another determinant of socioeconomic status and also correlates with parental occupation and education factors.

Previous studies have shown links between parental occupation and earnings and an overall increase in the volume of the brain’s grey matter.

However the study takes this further and shows that higher socioeconomic status in early childhood has a pronounced effect on two areas of the brain, the thalamus and striatum.

The thalamus is a key region in the centre of the brain involved in the transmission and processing of sensory information, and a larger thalamus volume is closely linked with quicker thinking and higher verbal IQ.

While differences in size and complexity of these brain regions tracked with socioeconomic status, and this has been shown to predict future life outcomes the study does not prove one causes the other.

Many other factors will play a role in early year;s development and future outcomes, and McDermott and colleagues say they hope understanding the roots in anatomy can help reduce variation.

ShredDaGnarGnar on December 27th, 2018 at 16:17 UTC »

Also see 'toxic stress' which is another facet of early childhood development obstacles for young children in poverty.

ABAyyy on December 27th, 2018 at 15:45 UTC »

There was research conducted by Hart and Risley that looked at the number of words a child was exposed to (in the home) across different socioeconomic statuses. They found there was a 30 million word gap!

A brief summary “in four years, an average child in a professional family would accumulate experience with almost 45 million words, an average child in a working-class family 26 million words, and an average child in a welfare family 13 million words”

I wonder if this may play a part in brain size?

Wiki 30 million word gap Wiki

mvea on December 27th, 2018 at 11:55 UTC »

The post title is a copy and paste from the title and subtitle of the linked popular press article here:

Childhood poverty has a lasting impact on developing brain, finds study

Brains of children whose parents have more education and so-called 'white collar jobs' are bigger in key areas

Journal Reference:

Longitudinally Mapping Childhood Socioeconomic Status Associations with Cortical and Subcortical Morphology

Cassidy L. McDermott, Jakob Seidlitz, Ajay Nadig, Siyuan Liu, Liv S. Clasen, Jonathan D. Blumenthal, Paul Kirkpatrick Reardon, François Lalonde, Deanna Greenstein, Raihaan Patel, M. Mallar Chakravarty, Jason P. Lerch, Armin Raznahan

Journal of Neuroscience 26 December 2018, 1808-18;

DOI: 10.1523/JNEUROSCI.1808-18.2018

Link: http://www.jneurosci.org/content/early/2018/12/26/JNEUROSCI.1808-18.2018

Abstract

Childhood socioeconomic status (SES) impacts cognitive development and mental health, but its association with human structural brain development is not yet well-characterized. Here, we analyzed 1243 longitudinally-acquired structural MRI scans from 623 youth (299 female/324 male) to investigate the relation between SES and cortical and subcortical morphology between ages 5 and 25 years. We found positive associations between SES and total volumes of the brain, cortical sheetnd four separate subcortical structures. These associations were stable between ages 5 and 25. Surface-based shape analysis revealed that higher SES is associated with areal expansion of (i) lateral prefrontalnterior cingulate, lateral temporalnd superior parietal cortices and (ii) ventrolateral thalamicnd medial amygdalo-hippocampal sub-regions. Meta-analyses of functional imaging data indicate that cortical correlates of SES are centered on brain systems subserving sensorimotor functions, language, memorynd emotional processing. We further show that anatomical variation within a subset of these cortical regions partially mediates the positive association between SES and IQ. Finally, we identify neuroanatomical correlates of SES that exist above and beyond accompanying variation in IQ. While SES is clearly a complex construct which likely relates to development through diverse, non-deterministic processes, our findings elucidate potential neuroanatomical mediators of the association between SES and cognitive outcomes.

SIGNIFICANCE STATEMENT

Childhood socioeconomic status (SES) has been associated with developmental disparities in mental health, cognitive abilitynd academic achievement, but efforts to understand underlying SES-brain relationships are ongoing. Here, we leverage a unique developmental neuroimaging dataset to longitudinally map the associations between SES and regional brain anatomy at high spatiotemporal resolution. We find widespread associations between SES and global cortical and subcortical volumes and surface areand localize these correlations to a distributed set of cortical, thalamicnd amygdalohippocampal subregions. Anatomical variation within a subset of these regions partially mediates the positive relationship between SES and IQ. Our findings help to localize cortical and subcortical systems which represent candidate biological substrates for the known relationships between SES and cognition.