The Daily Populous

Wednesday October 31st, 2018 evening edition

image for Xconomy: Pre-Existing Immunity to CRISPR Found in 96% of People in Study

Pre-Existing Immunity to CRISPR Found in 96% of People in Study.

(Cas9 from S. pyogenes is one of the most common DNA-cutting enzymes used in CRISPR R&D, if not the most commonly used.).

The researchers found that 96 percent of the people in the study had T-cell based immunity against Cas9, and 85% had antibodies against it.

Michael Schmueck-Henneresse of Charité University Medicine Berlin, who led today’s study, said that he was initially surprised by the 96% finding.

Intellia Therapeutics says it has been on the lookout for T-cell based immunity against its CRISPR system.

Other researchers have also raised a red flag around another CRISPR effect: unintended edits in off-target spots along the genome. »

Kanye West Tweets That He’s Taking A Break From Politics, Says He’s Being Used

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Kanye West is taking a step back from politics and says that he realizes now that he has been used to “spread messages” that he does not endorse.

At the same time, he laid out in a series of tweets that he supports gun control, prison reform, and immigration.

West posted on Twitter to clarify how he feels about several hot-button issues, saying that he supports common-sense laws that foster safety. »

Muslim groups raise enough money to cover funeral costs for all Pittsburgh victims - WBNS-10TV Columbus, Ohio | Columbus News, Weather & Sports

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Some of the money is already on the way to victims and their families, and organizers say they hope to cover the funeral costs for all 11 people who were killed.

The fundraiser on the site LaunchGood is a joint effort by the groups Celebrate Mercy and MPower Change.

The group hopes to cover the entirety of all funeral expenses for each of the victims, El-Messidi said, noting that Jewish funerals in the Pittsburgh area cost roughly $10,000. »

Has Mueller Subpoenaed the President?

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Brendan Smialowski/AFP/Getty Images ANALYSIS Has Mueller Subpoenaed the President?

Labor Day came and went without a visible move by Mueller to subpoena the president, and we entered the quiet period before the midterms.

Politico asked many of the known attorneys for Mueller witnesses—including Jay Sekulow, another Trump lawyer—and every one denied knowledge of the identity of the witness. »