The Daily Populous

Saturday May 12nd, 2018 evening edition

'Double Trojan Horse' Drug Tricks Bacteria into Committing Suicide
Authored by acsh.org
image for 'Double Trojan Horse' Drug Tricks Bacteria into Committing Suicide

A major reason is the cell wall: An antibiotic may be able to penetrate one type but not the other.

Finding new ways to sneak antibiotics past these cell wall barriers is one way that microbiologists are fighting antibiotic resistance.

Now, researchers have shown that a synthetic "double Trojan horse" drug can fool bacteria into willingly accepting a toxic antibiotic, essentially causing them to commit suicide.

Iron ions are not easy to come by, so some bacteria have evolved an elaborate mechanism to gather them.

Now, when the enzyme wielding bacterium destroys the first antibiotic, it unwittingly unleashes the second antibiotic, for which it has no defense.

The diagram below (which has been modified from the original) shows the mechanism by which the double Trojan horse drug works.

The bacterium, in this case the Gram-negative Acinetobacter, actively transports the double Trojan horse molecule across its first membrane. »

She didn't see it coming: psychic arrested for $800,000 fraud
Authored by theguardian.com
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Despite her self-proclaimed clairvoyance, a New York City psychic was arrested by the NYPD, in the latest example of fortune-teller fraud.

On 9 May the fortune-teller, whose real name is Ann Thompson, was arrested by the New York Police Department on suspicion of defrauding clients out of over $800,000.

She convinced the Canadian that she’d never find love again unless she bought the psychic a 9.2 carat diamond ring. »

The Last Slave Ship Survivor Gave an Interview in the 1930s. It Just Surfaced
Authored by history.com

Hurston’s book tells the story of Cudjo Lewis, who was born in what is now the West African country of Benin.

There, he and about 120 others were sold into slavery and crammed onto the Clotilda, the last slave ship to reach the continental United States.

Even though slavery was legal at that time in the U.S., the international slave trade was not, and hadn’t been for over 50 years. »

CHILDISH GAMBINO’S ‘THIS IS AMERICA’ HEADED FOR NO. 1 DEBUT
Authored by hiplegend.com
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According to projections, the politically-charged song is battling Drake’s “Nice for What” for the No. 1 spot on next week’s chart.

Gambino could draw 50 million U.S. streams, 8 million units with radio, and 60,000 downloads in his first week out.

These numbers could be enough to dethrone Drake’s “Nice for What,” which has remained No. 1 for four weeks. »

In pictures

image for Mario life
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image for Perfect circle in a tumbleweed.
image for The “Why do I feel like shit?” Starter Pack
image for Get on my level
image for The good year
image for Mods are asleep, stock up on supplies before the next fight.
image for This guys grand kids bought him this shirt
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image for This rooster always tries to get into the post office
image for OG Turtle trapping out the Gulf
image for My 1984 Mercedes Benz 300D, 381,000 miles and she’s still chugging along healthy. LED headlights and black trim just to add some personality to the old thing. Bought some years back for 1000 USD.
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image for Your brain can be a little too mean sometimes

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