The Daily Populous

Sunday February 25th, 2018 morning edition

image for Aβ, Then Metabolism, Then Atrophy: In Familial AD, Cascade is Definitive

Brian Gordon, Tyler Blazey, and colleagues at Washington University in St. Louis reported that this cascade emanated from the precuneus.

In general, Aβ accumulated first, then metabolism waned, then the cortex thinned, though some regions deviated from this sequence.

The precuneus succumbed first, accumulating Aβ more than 20 years before symptoms.

“[It] challenges us to look more closely at regional differences in the temporal time line of biomarkers,” she added.

Affected members develop early onset AD at an age researchers can predict based on family history and mutation.

The researchers fed both serial and cross-sectional data into a Bayesian statistical model to calculate annual rates of change for each marker.

Though Aβ deposition appeared long before the drop in glucose uptake in Gordon’s study, the researchers did not assess aerobic glycolysis specifically. »

Credible Amelia Earhart radio signals were ignored as bogus

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Dozens of previously dismissed radio signals were actually credible transmissions from Amelia Earhart, according to a new study of the alleged post-loss signals from Earhart's plane.

The transmissions started riding the air waves just hours after Earhart sent her last in-flight message.

"When the search failed, all of the reported post-loss radio signals were categorically dismissed as bogus and have been largely ignored ever since," he added. »

Amazon, Google and Apple under pressure to remove NRA streaming channel

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A screen shot of NRAtv, the streaming site of the National Rifle Association.

SAN FRANCISCO – Amazon, Apple, Google and Roku are under pressure to end streaming of the National Rifle Association's NRAtv following the Parkland, Fla. school shooting that killed 17.

Other video streaming products, including Google’s Chromecast, Apple TV, and Roku, were also under pressure to remove NRAtv from their services. »

Why are there so few $2 bills?

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She wanted to know why they're so rare, if they are worth more than $2 and if the government will ever stop printing them.

We took the question to John Bennardo, producer and director of an upcoming film called "The $2 Bill Documentary.".

The story of the $2 bill starts in 1862, when the federal government printed its first nationalized paper bills, Bennardo says. »