The modified poliovirus appears to enable T cells to attack cancer cells (shown here).
Researchers from Duke University in Durham, NC, may have discovered a new way of killing off cancer cells.
The new research - which is published in the journal Science Translational Medicine - shows how a modified poliovirus enables the body to use its own resources to fight off cancer.
The researchers examined the behavior of the poliovirus in two human cell lines: melanoma and triple-negative breast cancer.
Then, the poliovirus starts to attack the malignant cells, triggering the release of antigens from the tumor.
Antigens are toxic substances that the body does not recognize, therefore setting off an immune attack against them.
So, when the tumor cells release antigens, this alerts the body's immune system to start attacking. »